N-acetylcysteine in Severe COVID-19: The Possible Mechanism

Unravelling the Pathogenesis of Severe COVID-19 Pneumonia: Are There Possible Insights From High Altitude?

Immune Response to the Pathogenesis of COVID-19 Infection: Possible Mechanism of Nutrition (Vitamins, Supplement) and Exercise

COVID-19 infection, a present ravaging disease attributed to a SARS-CoV like illness has brought the world to it knee causing a pandemic, with human-human transmission indexed to be a major source of transmission of this ailment. Alarmingly, this infection based on clinical manifestations has been diagnosed as a virus induced pneumonia with over 5 million cases reckoned at a mortality rate of a...

A Review of the Possible Effects of Curcumin in the Treatment of COVID-19

COVID-19, which is caused by the SARS-Cov-2, begins with early symptoms of fever, cough, shortness of breath, myalgia, and fatigue, affecting the lungs with pneumonia and causing acute respiratory distress syndrome (ARDS). Also, the onset of the disease may with rapid progression, lead to organ dysfunction, such as acute kidney or liver damage, and even death in severe cases. Many scientific ef...

N-acetylcysteine in severe falciparum malaria in Thailand.

One hundred and eight patients with severe falciparum malaria underwent a placebo controlled trial with the antioxidant, N-acetylcysteine (NAC), as an adjunctive therapy along with standard intravenous artesunate therapy. Three NAC dosage regimens were used: an intravenous loading dose of 140 mg/kg followed by 70 mg/kg every four hours intravenously for up to 18 doses (Group 1); a single intrav...

Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis.

BACKGROUND Mortality among patients with severe acute alcoholic hepatitis is high, even among those treated with glucocorticoids. We investigated whether combination therapy with glucocorticoids plus N-acetylcysteine would improve survival. METHODS We randomly assigned 174 patients to receive prednisolone plus N-acetylcysteine (85 patients) or only prednisolone (89 patients). All patients rec...